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MOSTLY MICROBES AND INFECTIOUS DISEASES
Welcome to Mostly Microbes and Infectious Diseases. David Ojcius posts newspaper and journal articles in the broad field of microbiology.
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David Ojcius
Nov 3, 202310 min read
Lifestyle interventions to delay senescence
by Jan Martel, David M. Ojcius, John D. Young. #senescence is a condition of cell cycle arrest that increases #inflammation and...
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David Ojcius
Jun 8, 20233 min read
Taurine deficiency as a driver of aging
Studying various animals, a study found that the amount of the semi-essential amino acid #taurine in circulation decreased with age....
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David Ojcius
Jan 1, 20233 min read
A Drug to Treat Aging May Not Be a Pipe Dream
New approaches to the biology of #senescence can make lives longer and healthier. #aging #senolytics LIFE EXPECTANCY IN the...
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David Ojcius
Jun 8, 20211 min read
Senolytics reduce coronavirus-related mortality in old mice
#senescence #COVID19 #coronavirus #aging #inflammation Targeting senescent cells using senolytic drugs before or after coronavirus...
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David Ojcius
Apr 3, 20211 min read
The first non-invasive biomarker to track and verify efficacy of senolytic drugs
#senescence #aging Researchers have discovered a novel, non-invasive biomarker (15-deoxy-delta-12, 14-prostaglandin J2; dihomo-15d-PGJ2)...
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David Ojcius
Jan 16, 20211 min read
Targeting metabolism to influence aging
Glutamine has a host of metabolic functions, including biosynthesis, redox maintenance, and chromatin biology. Drugs are currently...
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David Ojcius
Jan 9, 20211 min read
Scientists develop new gene therapy strategy to delay aging
Researchers conducted genome-wide #CRISPR-based screens in premature aging stem cells & identified >100 candidate #senescence-promoting...
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David Ojcius
Dec 14, 20201 min read
Effects of Aging on Our Immune System
If you feel like you’re slowing down a bit as you age, you’re not alone. Many of our systems (including our brain) tend to taper off as...
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David Ojcius
Dec 12, 20201 min read
NAD boosting to reverse senescence and inflammaging.
Senescent cells promote NAD tissue decline during aging through CD38 enzymes which can now become a novel therapeutic target....
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