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MOSTLY MICROBES AND INFECTIOUS DISEASES
Welcome to Mostly Microbes and Infectious Diseases. David Ojcius posts newspaper and journal articles in the broad field of microbiology.
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David Ojcius
Mar 3, 20242 min read
Clinical development of antivirals against SARS-CoV-2 and its variants
Abstract The unceasing global spread of severe acute respiratory syndrome #coronavirus 2 (#SARSCoV2) calls for the development of novel...
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
David Ojcius
Sep 3, 20231 min read
A GWAS in the pandemic epicenter highlights severe COVID-19 risk locus introgressed by Neanderthals
Large GWAS indicated that genetic factors influence the response to #SARSCoV2. However, sex, age, concomitant diseases, differences in...
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David Ojcius
Jul 7, 20234 min read
Senolytics combat COVID-19 in aging
#aging increases vulnerability to respiratory viral infections, including by #SARSCoV2. Delval et al. established a causal role for...
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David Ojcius
May 7, 20232 min read
Infection of the oral cavity with SARS-CoV-2 variants: Scope of salivary diagnostics
Coronaviruses, including #SARSCoV2, have caused pandemics in the past two decades. The most prevalent SARS-CoV-2 variants of concern can...
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David Ojcius
Mar 12, 20231 min read
3D culture models to study SARS-CoV-2 infectivity and antiviral candidates: From spheroids to biopri
The pandemic caused by Severe Acute Respiratory Syndrome Coronavirus 2 (#SARSCoV2) is receiving worldwide attention, due to the severity...
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
David Ojcius
Nov 2, 20229 min read
Infection of the oral cavity with SARS-CoV-2 variants: Scope of salivary diagnostics
Coronaviruses, including #SARSCoV2, have caused pandemics in the past two decades. The most prevalent SARS-CoV-2 variants of concern can...
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
David Ojcius
Oct 1, 20226 min read
Fasting as key tone for COVID immunity
#SARSCoV2-induced #anorexia triggers systemic metabolic alterations. A new study shows that the ketone body β-hydroxybutyrate (BHB)...
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David Ojcius
Jul 23, 20226 min read
Operation Nasal Vaccine—Lightning speed to counter COVID-19
Just 10 months after the initial genome sequencing of the #SARSCoV2 virus, two mRNA vaccines were demonstrated to provide 95% efficacy...
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David Ojcius
Jun 11, 20223 min read
COVID and smell loss: answers begin to emerge
Smell disruption from #COVID19 is becoming less-common, but millions of people still have problems with their sense of #smell. The...
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David Ojcius
Jun 1, 20221 min read
Food allergy is associated with lower risk of SARS-CoV-2 infection
A study found that people with food #allergies are less likely to become infected with the #SARSCoV2 #coronavirus. The study also found...
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
David Ojcius
Apr 6, 20224 min read
What triggers severe COVID? Infected immune cells hold clues
Two studies show that immune cells infected with #SARSCoV2 can stimulate a large inflammatory response via #inflammasome activation. In...
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David Ojcius
Mar 21, 20228 min read
Scientists struggle to probe COVID’s origins amid sparse data from China
3 recent preprints offer further evidence supporting the hypothesis that the #coronavirus spread from animals to people. A next step in...
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David Ojcius
Mar 12, 20221 min read
Covid Cases Linked to Brain Shrinkage, Cognitive Decline Months Later
Even a mild case of #COVID19 can damage the brain, leading to shrinkage equivalent to up to a decade of #aging, according to a new study....
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David Ojcius
Mar 5, 20222 min read
First Possible Case of Covid-19 Spreading From Deer to Humans
Scientists in Canada discovered the 1st potential case of deer passing #coronavirus to a human, according to a preprint. The discovery...
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David Ojcius
Feb 3, 20225 min read
In New York City Sewage, a Mysterious Coronavirus Signal
New York City’s #wastewater contains #coronavirus sequences with unique mutations that have not been reported in human patients. There...
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David Ojcius
Jan 26, 20222 min read
Long-COVID symptoms less likely in vaccinated people, Israeli data say
#LongCovid symptoms less likely in vaccinated people, Israeli data say. People who have had both #SARSCoV2 #coronavirus infection &...
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David Ojcius
Dec 24, 20211 min read
Evolution of enhanced innate immune evasion by SARS-CoV-2
Evolution of enhanced innate immune evasion by the #SARSCoV2 #coronavirus. "Importance of mutations outside Spike in adaptation of...
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David Ojcius
Dec 17, 20212 min read
Making it easier to be a patient in times of a pandemic
by David Chambers, Michelle Brady, David Ojcius, Evelyn Cuny #COVID19 #COVID #SARSCoV2 #coronavirus #dentistry #dental 1 PROBLEM What...
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David Ojcius
Dec 12, 20212 min read
Signs of the Omicron variant are being found in California wastewater systems
In the effort to track the spread of #SARSCoV2 #coronavirus, researchers are monitoring #wastewater in many locations around the state of...
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David Ojcius
Nov 11, 20213 min read
How SARS-CoV-2 in American deer could alter the course of the global Covid pandemic
A new study (not peer-reviewed yet) shows evidence that the #SARSCoV2 #coronavirus spreads widely in white-tailed deer, & the virus is...
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