Highlights A classically anaerobic pathogen creates and thrives in a localized oxidative niche BFT rewires epithelial metabolism from oxidative phosphorylation to fermentation Host metabolic rewiring increases lactate and oxygen in the ETBF niche BFT enables ETBF to adapt to this oxidative niche and promote colonization Summary To colonize their host and cause disease, enteric pathogens must deploy their virulence factors to establish distinct nutrient niches. How anaerobic p

Highlights The transition from a planktonic to a sessile lifestyle in Anabaena sp. PCC 7120 is driven by a massive transcriptomic reprogramming involving 17.7% of the genome. Sessile growth involves cell envelope remodeling and lower anabolic activity. While nitrogen deficiency and salinity promote biofilm formation, iron deficiency exerts contrasting effects on sessile development. Stress-adaptation pathways are directly linked to biofilm development. Abstract Cyanobacteria

ABSTRACT Deoxyribonucleic acid (DNA) is naturally contained within the mitochondria and nucleus of cells. DNA localized outside of these areas is generally considered to constitute damage-associated molecular patterns (DAMP) that trigger innate immune responses. The variety of these immune-stimulatory nucleic acids, coupled with the variety of proteins known to interact with DNA DAMPS and to act as sensors or regulators, is an important layer of regulation that defines the na

Highlights Climate change and environmental stressors are major drivers affecting global food security and agricultural sustainability. Microbial communities play a central role in nutrient cycling, plant health, and ecosystem resilience. Climate variability alters microbial diversity, functions, and plant–microbe interactions. Beneficial microorganisms enhance crop tolerance to abiotic and biotic stresses. Microbiome-based strategies offer sustainable alternatives to chemica