Highlights Dietary soy enhances L. reuteri and M. intestinale colonization in the small intestine Dietary soy promotes Tfh cell and IgA responses in the Peyer’s patches of weaning mice L. reuteri provides cognate antigens, while M. intestinale drives IL-1β production Soy-induced IgA is polyreactive and protects against Salmonella infection Summary The commensal microbiota plays a crucial role in shaping mucosal immunity, particularly in the induction of T follicular helper (T

Highlights CheW2 negatively regulated the expression of outer membrane proteins in V. splendidus ClpP degraded CheW2 based on the recognization of its AA motif at the N terminal Pseudoalteromonas sp. H2 attenuated the expression of clpP gene of V. splendidus AJ01 Abstract In mariculture ecosystems where Vibrio spp. are predominant pathogens, effective biocontrol through antagonistic probiotics remains an unresolved biological challenge. Here, the Pseudoalteromonas sp. H2 stra

Highlights Sesame-flavor Baijiu fermentation was performed using different sorghum varieties. Microbial interactions affected volatile formation differently in sorghum varieties. Cultivar-specific physicochemical traits modulate microbial consortia structure. Sorghum selection can format flavor paradigm and standardize Baijiu quality. Abstract Sorghum is a key raw ingredient in the fermentation of Sesame-flavor Baijiu (SFB). However, studies on the microbial and metabolic dyn

Highlights This study systematically analyzed alterations in the ocular surface microbiome of patients with progressive supranuclear palsy-Richardson’s syndrome (PSP-RS) via metagenomic sequencing, with comparisons to Parkinson’s disease (PD) patients and healthy controls (HC). The β-diversity of the ocular surface microbiome in PSP-RS patients was significantly altered compared to HC, while no such obvious difference was observed in PD patients. PSP-RS patients exhibited inc