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MOSTLY MICROBES AND INFECTIOUS DISEASES
Welcome to Mostly Microbes and Infectious Diseases. David Ojcius posts newspaper and journal articles in the broad field of microbiology.

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Role of Medicine and Technology in Shaping the Future of Oral Health
This commentary describes the changes taking place in dentistry and speculates on improvements that could happen soon. Advances in health care will have an impact on the integration and delivery of oral care; conversely, there is growing acceptance that oral health impacts systemic health. Technological innovations are changing the face of medical care and are quickly becoming integrated into dentistry. Advances in novel antimicrobials, genomics, robotics and artificial intel
David Ojcius
6 hours ago1 min read
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Major Histocompatibility Complex Class I Molecules and Resistance against Intracellular Pathogens
The immune system employs a temporal hierarchy of effector mechanisms to combat infections by intracellular pathogens. The nonspecific response is independent of MHC and can be activated rapidly, while the specific response is slower, more specific, and requires major histocompatibility complex (MHC) molecules. MHC-dependent responses have been characterized extensively in vitro  for antigens presented by polymorphic MHC class la and class II proteins and recognized by T lym
David Ojcius
2 days ago1 min read
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Effects of Frankincense Compounds on Infection, Inflammation, and Oral Health (Review Article)
Boswellia  trees, found throughout the Middle East and parts of Africa and Asia, are the source of frankincense oil. Since antiquity, frankincense has been traded as a precious commodity, but it has also been used for the treatment of chronic disease, inflammation, oral health, and microbial infection. More recently, the bioactive components of Boswellia  trees have been identified and characterized for their effects on cancer, microbial infection (especially infection by or
David Ojcius
Nov 81 min read
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History of dental treatments
The history of dental treatments  dates back to thousands of years. [1] [2]  The scope of this article is limited to the pre-1981 history . The earliest known example of dental caries  manipulation is found in a Paleolithic  man, dated between 14,160 and 13,820 BP . [3]  The earliest known use of a filling  after removal of decayed or infected pulp  is found in a Paleolithic who lived near modern-day Tuscany , Italy, from 13,000 to 12,740 BP. [4]  Although inconclusiv
David Ojcius
Oct 162 min read
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Boca humana
La boca , también denominada como una cavidad bucal  o cavidad oral,  siendo en realidad divisiones en sà de la boca del aparato digestivo; [1] ​ es la abertura corporal por la que se ingieren alimentos . [2] ​ Está ubicada en la cara  y constituye en su mayor parte el aparato estomatognático , asà como la primera parte del aparato digestivo . La boca se abre a un espacio previo a la faringe  llamado cavidad oral, o cavidad bucal. La boca humana  está cubierta por lo
David Ojcius
Oct 141 min read
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Visit of University of Gujrat dean sparks collaboration with Pacific University
Dean Prof. Dr. Zahid Yousaf of the University of Gujrat (UOG) embarked on a significant visit to the University of the Pacific,...
David Ojcius
Oct 122 min read
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Exercise-induced microbiota metabolite enhances CD8 T cell antitumor immunity promoting immunotherapy efficacy
Highlights • Exercise-induced microbial formate enhances immune checkpoint inhibitor efficacy • Microbiota-derived formate is essential...
David Ojcius
Oct 41 min read
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The Effects of Frankincense on Oral Health
Frankincense oil, originating from Boswellia trees in the Middle East, Africa, and parts of Asia, has a rich history as a valuable remedy...
David Ojcius
Oct 42 min read
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Antimicrobial effects of frankincense extracts on oral pathogens
Introduction: Boswellia trees are the source of frankincense extracts that can be found throughout the Middle East and parts of Africa...
David Ojcius
Sep 293 min read
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The impact of oral health disparities on smoking prevalence
Smoking increases the risk of heart disease, cancer, lung infections, and diabetes, and causes oral health problems. The prevalence of...
David Ojcius
Sep 261 min read
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Capitalisation (Composante 3 – Équipact), EQUIPer les ACTeurs pour plus d’impact dans les transitions
Cette composante s’est appuyée sur la méthodologie développée par l’association RESOLIS, à savoir une méthode d’analyse systématique et...
David Ojcius
Sep 183 min read
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Role of the P2X7 receptor in intestinal inflammation due to infection with the oral pathogen Porphyromonas gingivalis
Highlights P . gingivalis upregulated P2X7 receptor levels in the colon of wildtype mice. P . gingivalis triggered intestinal...
David Ojcius
Sep 162 min read
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Tribute to the Institut Pasteur in Genes & Immunity
On the occasion of the high-level meeting showcasing 130 years of Science at the Institut Pasteur, the Genes & Immunity Journal published...
David Ojcius
Sep 61 min read
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Genes & Immunity rend hommage à l’Institut Pasteur
La revue Genes & Immunity  publie, à l’occasion de la rencontre au sommet célébrant 130 ans de recherche à l’Institut Pasteur, un numéro...
David Ojcius
Sep 61 min read
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Announcing the "Pacific Journal of Health"
There is a growing number of health-related programs at the University of the Pacific on the three campuses - in Stockton, San Francisco...
David Ojcius
Aug 311 min read
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A T cell-based Ubiquitin-mediated mRNA Vaccine Provides Cross-Protection Against H1N1 and B Influenza Viruses in Mice
Highlights A novel mRNA vaccine was developed to achieve broad-spectrum protection against Influenza virus. The Ub-Re-N mRNA vaccine...
David Ojcius
Aug 102 min read
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Comprehensive human proteome profiles across a 50-year lifespan reveal aging trajectories and signatures
Highlights • A proteomic blueprint of human organs across 50-year aging stages • Transcriptome-proteome decoupling and proteostasis...
David Ojcius
Jul 291 min read
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Microplastics and antibiotic resistance genes as rising threats
Highlights MPs and ARGs build up in organisms, posing a risk to human health through the food chain. Plastic ball communities on MPs...
David Ojcius
Jul 231 min read
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Jeunes chercheurs : éduquer par la recherche, expérience avec une classe de lycéens de seconde à Villejuif
Ce projet propose d’accompagner un groupe de jeunes pour leur apprendre à penser leurs préoccupations en termes d’objets de recherche. Il...
David Ojcius
Jul 192 min read
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Exercise-induced microbiota metabolite enhances CD8 T cell antitumor immunity promoting immunotherapy efficacy
Highlights • Exercise-induced microbial formate enhances immune checkpoint inhibitor efficacy • Microbiota-derived formate is essential...
David Ojcius
Jul 101 min read
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